Publications

Data updated monthly from CIÊNCIAVITAE.

Books

2013

Luo, Y.; Engelmayr, G.; Auguste, D.T.; da Silva Ferreira, L.; Karp, J.M.; Saigal, R.; Langer, R.

3D Scaffolds ↗

2013

Khademhosseini, A.; Karp, J.M.; Gerecht-Nir, S.; Ferreira, L.; Annabi, N.; Sirabella, D.; Vunjak-Novakovic, G.; Langer, R.

Embryonic Stem Cells as a Cell Source for Tissue Engineering ↗

2013

2011

Spelke, D.P.; Ortmann, D.; Khademhosseini, A.; Ferreira, L.; Karp, J.M.

Methods for embryoid body formation: The microwell approach ↗

2011

2007

Khademhosseini, A.; Karp, J.M.; Gerecht, S.; Ferreira, L.; Vunjak-Novakovic, G.; Langer, R.

Embryonic stem cells as a cell source for tissue engineering ↗

2007

Karp, J.M.; Mahdavi, A.; Ferreira, L.S.; Khademhosseini, A.; Langer, R.

Part C: Directed Differentiation of Human Embryonic Stem Cells into Osteoblasts Cells ↗

2007

Luo, Y.; Engelmayr, G.; Auguste, D.T.; Ferreira, L.D.S.; Karp, J.M.; Saigal, R.; Langer, R.

Three-dimensional scaffolds ↗

2007

Book Chapters

2022

Deolinda Santinha, Andreia Vilaça, Alessandro Ori, Lino Ferreira. Corresponding author: Deolinda Santinha, Andreia Vilaça, Alessandro Ori, Lino Ferreira

The Extracellular Matrix in Cardiovascular Aging¿ ↗

Elsevier, 2022

2020

Ali Khademhossein, Nureddin Ashammakhi, Jeffrey M. Karp, Sharon Gerecht-Nir, Lino Ferreira, Nasim Annab, Mohammad Ali Da

Embryonic stem cells as a cell source for tissue engineering ↗

Academic Press, 2020

2019

Rai, Akhilesh; Comune, Michela; Ferreira, Lino

Nanoparticle-Based Drug Delivery Systems: Promising Approaches Against Bacterial Infections ↗

Springer Singapore, 2019

2018

Pitrez, Patrícia R.; Aires, Helena R.; Tomé, Inês; Ferreira, Rita Sá; Ferreira, Lino

Physiological and Pathological Vascular Aging ↗

Springer International Publishing, 2018

2016

Estronca, L.; Ferreira, L.

Stem Cells for the Regeneration of Chronic Wounds ↗

Elsevier, 2016

Conference Papers

2011

Paulo, C.; Vidal, M.; Ferreira, L.

Antifungal nanoparticles and surfaces

2011

Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells in a fibrin gel

2011

2008

Zumbuehl, A.; Ferreira, L.; Kuhn, D.; Astashkina, A.; Long, L.; Yeo, Y.; Iaconis, T.; et al

Antifungal hydrogels

2008

Ferreira, L.; Squier, T.; Park, H.; Choe, H.; Kohane, D.S.; Langer, R.

Human embryoid bodies containing particulate delivery vehicles

2008

Journal Articles

2024

Patricia R. Pitrez; Luis M. Monteiro; Oliver Borgogno; Xavier Nissan; Jerome Mertens; Lino Ferreira

Cellular reprogramming as a tool to model human aging in a dish ↗

Nature Communications, 2024

Andreia Vilaça; Carlos Jesus; Miguel Lino; Danika Hayman; Costanza Emanueli; Cesare M. Terracciano; Hugo Fernandes; Leon J. de Windt; Lino Ferreira

Extracellular vesicle transfer of lncRNA H19 splice variants to cardiac cells ↗

Molecular Therapy - Nucleic Acids, 2024

Emanuel Quartin; Susana Rosa; Sara Gonzalez-Anton; Laura Mosteo Lopez; Vitor Francisco; Delfim Duarte; Cristina Lo Celso; Ricardo Pires das Neves; Lino Ferreira

Nanoparticle-encapsulated retinoic acid for the modulation of bone marrow hematopoietic stem cell niche ↗

Bioactive Materials, 2024

Simões, Susana; Lino, Miguel; Barrera, Angela; Rebelo, Catarina; Tomatis, Francesca; Vilaça, Andreia; Breunig, Christopher; et al

Near-Infrared Light Activated Formulation for the Spatially Controlled Release of CRISPR-Cas9 Ribonucleoprotein for Brain Gene Editing ↗

Angewandte Chemie International Edition, 2024

Preto, António J.; Caniceiro, Ana B.; Duarte, Francisco; Fernandes, Hugo; Ferreira, Lino; Mourão, Joana; Moreira, Irina S.

POSEIDON: Peptidic Objects SEquence-based Interaction with cellular DOmaiNs: a new database and predictor ↗

Journal of Cheminformatics, 1, 2024

Santinha, Deolinda; Vilaça, Andreia; Estronca, Luís; Schüler, Svenja C.; Bartoli, Catherine; De Sandre-Giovannoli, Annachiara; Figueiredo, Arnaldo; et al

Remodeling of the Cardiac Extracellular Matrix Proteome During Chronological and Pathological Aging

Mol Cell Proteomics, 1, 100706-, 2024

Kelly, George; Kataura, Tetsushi; Panek, Johan; Ma, Gailing; Salmonowicz, Hanna; Davis, Ashley; Kendall, Hannah; et al

Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule ↗

Developmental Cell, 2024

2023

Seena S; Ferrão R; Pala M; Roelants SLKW; Soetaert W; Stevens CV; Ferreira L; Rai A

Acidic sophorolipid and antimicrobial peptide based formulation as antimicrobial and antibiofilm agents. ↗

Biomaterials advances, 2023

Catarina Rebelo; Tiago Reis; Joana Guedes; Cláudia Saraiva; Artur Filipe Rodrigues; Susana Simões; Liliana Bernardino; et al

Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications ↗

Nature Communications, 2023

González, Ricardo D.; Simões, Susana; Ferreira, Lino; Carvalho, Alexandra T. P.

Designing Cell Delivery Peptides and SARS-CoV-2-Targeting Small Interfering RNAs: A Comprehensive Bioinformatics Study with Generative Adversarial Network-Based Peptide Design and <i>In Vitro</i> Assays ↗

Molecular Pharmaceutics, 12, 6079-, 2023

Artur Filipe Rodrigues; Ana P. M. Tavares; Susana Simões; Rui P. F. F. Silva; Tomás Sobrino; Bruno R. Figueiredo; Goreti Sales; Lino Ferreira

Engineering graphene-based electrodes for optical neural stimulation ↗

Nanoscale, 2023

Artur Filipe Rodrigues; Catarina Rebelo; Tiago Reis; Susana Simões; Liliana Bernardino; João Peça; Lino Ferreira

Engineering optical tools for remotely controlled brain stimulation and regeneration ↗

Biomaterials Science, 2023

Banerjee, Arnab; Lino, Miguel; Jesus, Carlos; Ribeiro, Quélia; Abrunhosa, Antero; Ferreira, Lino

Imaging platforms to dissect the in vivo communication, biodistribution and controlled release of extracellular vesicles ↗

Journal of Controlled Release, 549-, 2023

Federico Traldi; Liu P; Inês Maria Cunha Albino; Ferreira L; Ali Zarbakhsh; Marina Resmini

Protein-Nanoparticle Interactions Govern the Interfacial Behavior of Polymeric Nanogels: Study of Protein Corona Formation at the Air/Water Interface. ↗

International journal of molecular sciences, 2023

Sousa JA; Bernardes C; Bernardo-Castro S; Lino M; Albino I; Ferreira L; Brás J; et al

Reconsidering the role of blood-brain barrier in Alzheimer's disease: From delivery to target. ↗

Frontiers in aging neuroscience, 2023

Marta Pereira; Alba Grayston; Miguel García-Gabilondo; Vitor Francisco; Ana Clara Cristovao; João Pedro Marto; Helena L. A. Vieira; et al

Retinoic Acid-Loaded Nanoparticles Promote Neurovascular Protection in Stroke. ↗

Stroke, 2023

Lino, Miguel M.; Rondão, Tiago; Banerjee, Arnab; Aires, Inês; Rodrigues, Magda; Reis, Tiago; Santinha, António; et al

Small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model ↗

Nanoscale, 45, 18212-, 2023

Sara Bernardo-Castro; João André Sousa; Martins E; Helena Donato; Nunes CA; d'Almeida OC; Miguel Castelo-Branco; et al

The evolution of blood brain barrier permeability changes after stroke, and its implications on clinical outcome: a systematic review and meta-analysis. ↗

International journal of stroke : official journal of the International Stroke Society, 2023

2022

Jusic A; Stellos K; Ferreira L; Baker AH; Devaux Y

(Epi)transcriptomics in cardiovascular and neurological complications of COVID-19. ↗

Journal of molecular and cellular cardiology plus, 2022

A NIR-II emissive polymer AIEgen for imaging-guided photothermal elimination of bacterial infection ↗

Biomaterials, 121579-, 2022

Artur Filipe Rodrigues; Catarina Rebelo; Susana Simões; Cristiana Paulo; Sónia Pinho; Vítor Francisco; Lino Ferreira

A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts ↗

Advanced Science, 2022

Akhilesh Rai; Rafaela Ferrão; Paulo Palma; Tatiana Patricio; Paula Parreira; Elsa Anes; Chiara Tonda-Turo; et al

Antimicrobial peptide-based materials: opportunities and challenges ↗

Journal of Materials Chemistry B, 2022

Akhilesh Rai; Rafaela Ferrão; Denise Marta; Andreia Vilaça; Miguel Lino; Tiago Rondão; Jian Ji; Artur Paiva; Lino Ferreira

Antimicrobial Peptide-Tether Dressing Able to Enhance Wound Healing by Tissue Contact ↗

ACS Applied Materials & Interfaces, 2022

Catarina Rebelo; Tiago Reis; Joana Guedes; Cláudia Saraiva; Artur Filipe Rodrigues; Susana Simões; Liliana Bernardino; et al

Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications ↗

Nature Communications, 2022

Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration ↗

Molecular Therapy - Nucleic Acids, 307-, 2022

Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells ↗

Molecular Therapy, 6, 2257-, 2022

MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease ↗

Molecular Therapy, 2022

Multi-parametric surface plasmon resonance-based intake quantification of label-free light-activated nanoparticles by therapeutic limbal stem cells for corneal blindness ↗

Nano Select, 2022

Vilaça A; de Windt LJ; Hugo Fernandes; Ferreira L

Strategies and challenges for non-viral delivery of non-coding RNAs to the heart. ↗

Trends in molecular medicine, 2022

Custodia A; Ouro A; Sargento-Freitas J; Aramburu-Núñez M; Pías-Peleteiro JM; Pablo Hervella; Rosell A; et al

Unraveling the potential of endothelial progenitor cells as a treatment following ischemic stroke. ↗

Frontiers in neurology, 2022

2021

Michela Comune; Akhilesh Rai; Paulo Palma; Chiara TondaTuro; Lino Ferreira

Antimicrobial and pro-angiogenic properties of soluble and nanoparticle-immobilized LL37 peptides ↗

Biomaterials Science, 2021

Rai, Akhilesh; Ferreira, Lino

Biomedical applications of the peptide decorated gold nanoparticles ↗

Critical Reviews in Biotechnology, 2, 186-, 2021

Lino, Miguel M.; Simões, Susana; Tomatis, Francesca; Albino, Inês; Barrera, Angela; Vivien, Denis; Sobrino, Tomas; Ferreira, Lino

Engineered extracellular vesicles as brain therapeutics ↗

Journal of Controlled Release, 472-, 2021

Abreu, Ricardo C.; Ramos, Cristiana V.; Becher, Clarissa; Lino, Miguel; Jesus, Carlos; Costa Martins, Paula A.; Martins, Patrícia A. T.; et al

Exogenous loading of miRNAs into small extracellular vesicles ↗

Journal of Extracellular Vesicles, 10, 2021

Inês Tomé; Vitor Francisco; Hugo Fernandes; Lino Ferreira

High-throughput screening of nanoparticles in drug delivery ↗

APL Bioengineering, 2021

Almeida, Henrique V.; Tenreiro, Miguel F.; Louro, Ana F.; Abecasis, Bernardo; Santinha, Deolinda; Calmeiro, Tomás; Fortunato, Elvira; et al

Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation ↗

ACS Applied Bio Materials, 2, 1888-, 2021

Estronca, Luís; Francisco, Vitor; Pitrez, Patrícia; Honório, Inês; Carvalho, Lara; Vazão, Helena; Blersch, Josephine; et al

Induced pluripotent stem cell-derived vascular networks to screen nano–bio interactions ↗

Nanoscale Horizons, 2021

Tenreiro, Miguel F.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Ferreira, Lino; Alves, Paula M.; Serra, Margarida

Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization ↗

Scientific Reports, 1, 2021

Pires, Cristiana L.; Praça, Catarina; Martins, Patrícia A. T.; Batista de Carvalho, Ana L. M.; Ferreira, Lino; Marques, Maria Paula M.; Moreno, Maria João

Re-Use of Caco-2 Monolayers in Permeability Assays—Validation Regarding Cell Monolayer Integrity ↗

Pharmaceutics, 10, 1563-, 2021

Rui F. Simões; Rafaela Ferrão; Margarida R. Silva; Sonia L.C. Pinho; Lino Ferreira; Paulo J. Oliveira; Teresa Cunha-Oliveira

Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research ↗

Food and Chemical Toxicology, 111967-, 2021

João Conniot; Sepehr Talebian; Susana Simões; Lino Ferreira; João Conde

Revisiting gene delivery to the brain: silencing and editing ↗

Biomaterials Science, 4, 1065-, 2021

Bernardo-Castro, Sara; Albino, Inês; Barrera-Sandoval, Ángela María; Tomatis, Francesca; Sousa, João André; Martins, Emanuel; Simões, Susana; et al

Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke ↗

Life, 6, 482-, 2021

2020

Francisco, Vitor; Rebelo, Catarina; Rodrigues, Artur Filipe; Blersch, Josephine; Fernandes, Hugo; Ferreira, Lino

A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies ↗

Methods, 2020

Josephine Blersch; Vitor Francisco; Catarina Rebelo; Adrian Jiménez-Balsa; Helena Antunes; Sandra Pinto; Susana Simões; Akhilesh Rai; Lino Ferreira

A light-triggerable formulation to control the stability of pro-angiogenic transcription factor hypoxia inducible factor-1a (HIF-1a) ↗

Nanoscale, 2020

Blersch, Josephine; Francisco, Vitor; Rebelo, Catarina; Jiménez-Balsa, Adrian; Antunes, Helena; Gonzato, Carlo; Pinto, Sandra; et al

A Light-Triggerable Nanoparticle Library for the Controlled Release of Non-Coding RNAs ↗

Angewandte Chemie International Edition, 5, 1985-, 2020

Raquel Ferreira; Joseph Napoli; Tariq Enver; Liliana Bernardino; Lino Ferreira

Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine ↗

Nature Communications, 2020

de Abreu RC; Fernandes H; da Costa Martins PA; Sahoo S; Emanueli C; Ferreira L

Native and bioengineered extracellular vesicles for cardiovascular therapeutics. ↗

Nature reviews. Cardiology, 2020

Bernardo-Castro, Sara; Sousa, João André; Brás, Ana; Cecília, Carla; Rodrigues, Bruno; Almendra, Luciano; Machado, Cristina; et al

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery ↗

Frontiers in Neurology, 2020

Ferreira, Lino

Permeability of the blood brain barrier through the phases of ischemic stroke and relation with clinical outcome: protocol for a systematic review

BMJ Open, 9, e039280-, 2020

Buczak K; Kirkpatrick JM; Truckenmueller F; Santinha D; Ferreira L; Roessler S; Singer S; Beck M; Ori A

Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry. ↗

Nature protocols, 2020

Pitrez PR; Estronca L; Monteiro LM; Colell G; Vazão H; Santinha D; Harhouri K; et al

Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13. ↗

Nature communications, 2020

2019

Ferreira, Lino

A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity ↗

Current Protocols in Stem Cell Biology, 2019

Ferreira, Lino

A light-triggerable nanoparticle library for the controlled release of non-coding RNAs. ↗

Angewandte Chemie (International ed. in English), 2019

Ferreira, Lino

A near infrared light-triggerable modular formulation for the delivery of small biomolecules ↗

Journal of Nanobiotechnology, 2019

Tian-tian Yao; Jing Wang; Yun-fan Xue; Wei-jiang Yu; Qiang Gao; Lino Ferreira; Ke-Feng Ren; Jian Ji

A photodynamic antibacterial spray-coating based on the host–guest immobilization of the photosensitizer methylene blue ↗

Journal of Materials Chemistry B, 2019

Arnab Banerjee; Vitor Alves; Tiago Rondão; José Sereno; Ângela Neves; Miguel Lino; Andreia Ribeiro; Antero J. Abrunhosa; Lino S. Ferreira

A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles ↗

Nanoscale, 28, 13243-, 2019

Ferreira, Lino

Bioprocess decision support tool for scalable manufacture of extracellular vesicles ↗

Biotechnology and Bioengineering, 2019

Ferreira, Lino

Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells. ↗

Stem cell reports, 2019

Ferreira, Lino

Functional characterization of iPSC-derived arterial- and venous-like endothelial cells ↗

Scientific Reports, 2019

Ferreira, Lino

Spatially Confining Surface Roughness on Exponentially Growing Polyelectrolyte Multilayer Films ↗

Advanced Materials Interfaces, 2019

Ferreira, Lino

The Kinetics of Small Extracellular Vesicle Delivery Impacts Skin Tissue Regeneration ↗

ACS Nano, 2019

Bernardo Abecasis; Patrícia Gomes-Alves; Susana Rosa; Pedro J. Gouveia; Lino Ferreira; Margarida Serra; Paula M. Alves

Unveiling the molecular crosstalk in a human induced pluripotent stem cell-derived cardiac model ↗

Biotechnology and Bioengineering, 5, 1245-, 2019

Ferreira, Lino

What human blood-brain barrier models can tell us about BBB function and drug discovery? ↗

Expert opinion on drug discovery, 2019

2018

Ferreira, Lino

A nanoformulation for the preferential accumulation in adult neurogenic niches ↗

Journal of Controlled Release, 2018

André F. Ferreira; Michela Comune; Akhilesh Rai; Lino Ferreira; Pedro N. Simões

Atomistic-Level Investigation of a LL37-Conjugated Gold Nanoparticle By Well-Tempered Metadynamics ↗

The Journal of Physical Chemistry B, 2018

Ferreira, Lino

Cecropin-Melittin Functionalized Polyurethane Surfaces Prevent Staphylococcus epidermidis Adhesion without Inducing Platelet Adhesion and Activation ↗

Advanced Materials Interfaces, 2018

Ferreira, Lino

Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming ↗

Cell Reports, 2018

Sargento-Freitas J; Aday S; Nunes C; Cordeiro M; Gouveia A; Silva F; Machado C; et al

Endothelial progenitor cells enhance blood-brain barrier permeability in subacute stroke. ↗

Neurology, 2018

Ferreira, Lino

Endothelial Progenitor Cells influence acute and subacute stroke hemodynamics ↗

Journal of the Neurological Sciences, 2018

Ferreira, Lino

Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain ↗

Neuroscience Letters, 2018

Lino MM; Ferreira L

Light-triggerable formulations for the intracellular controlled release of biomolecules. ↗

Drug discovery today, 2018

Ferreira, Lino

MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo ↗

PLOS ONE, 2018

Miguel M. Lino; Susana Simões; Andreia Vilaça; Helena Antunes; Alessandra Zonari; Lino Ferreira

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers ↗

ACS Nano, 2018

Adrián Jiménez-Balsa; Sandra Pinto; Emanuel Quartin; Miguel M. Lino; Vitor Francisco; Lino Ferreira

Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules ↗

Bioconjugate Chemistry, 2018

Ferreira, Lino

Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation ↗

Scientific Reports, 2018

Pinho S; Macedo MH; Rebelo C; Sarmento B; Ferreira L

Stem cells as vehicles and targets of nanoparticles. ↗

Drug discovery today, 2018

Ferreira, Lino

STROKE34 Study Protocol: A Randomized Controlled Phase IIa Trial of Intra-Arterial CD34+ Cells in Acute Ischemic Stroke ↗

Frontiers in Neurology, 2018

Patricia R. Pitrez; Luís Estronca; Helena Vazão; Anne-Laure Egesipe; Amélie Le Corf; Claire Navarro; Nicolas Lévy; et al

Substrate Topography Modulates Cell Aging on a Progeria Cell Model ↗

ACS Biomaterials Science & Engineering, 2018

2017

Ferreira, Lino

Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded Nanoparticles ↗

Mediators of Inflammation, 2017

Comune M; Rai A; Chereddy KK; Pinto S; Aday S; Ferreira AF; Zonari A; et al

Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential. ↗

Journal of controlled release : official journal of the Controlled Release Society, 2017

Ribas J; Zhang YS; Pitrez PR; Leijten J; Miscuglio M; Rouwkema J; Dokmeci MR; et al

Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model. ↗

Small (Weinheim an der Bergstrasse, Germany), 2017

Santos T; Ferreira R; Quartin E; Boto C; Saraiva C; Bragança J; Peça J; et al

Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles. ↗

Acta biomaterialia, 2017

Machado-Pereira M; Santos T; Ferreira L; Bernardino L; Ferreira R

Challenging the great vascular wall: Can we envision a simple yet comprehensive therapy for stroke? ↗

Journal of tissue engineering and regenerative medicine, 2017

Monteiro LM; Vasques-Nóvoa F; Ferreira L; Pinto-do-Ó P; Nascimento DS

Erratum: Restoring heart function and electrical integrity: Closing the circuit. ↗

NPJ Regenerative medicine, 2017

Ribeiro-Rodrigues TM; Laundos TL; Pereira-Carvalho R; Batista-Almeida D; Pereira R; Coelho-Santos V; Silva AP; et al

Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis. ↗

Cardiovascular research, 2017

Ferreira, Lino

Findings on the interaction of the antimicrobial peptide cecropin-melittin with a gold surface from molecular dynamics studies ↗

European Biophysics Journal, 2017

Gouveia PJ; Rosa S; Ricotti L; Abecasis B; Almeida HV; Monteiro L; Nunes J; et al

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes. ↗

Biomaterials, 2017

Vazão H; Rosa S; Barata T; Costa R; Pitrez PR; Honório I; de Vries MR; et al

High-throughput identification of small molecules that affect human embryonic vascular development. ↗

Proceedings of the National Academy of Sciences of the United States of America, 2017

Miguel M. Lino; Susana Simões; Sónia Pinho; Lino Ferreira; Lino MM; Simões S; Pinho S; Ferreira L

Intracellular delivery of more than one protein with spatio-temporal control ↗

Nanoscale, 47, 18668-, 2017

Boto, Carlos; Quartin, Emanuel; Cai, Yijun; Martín-Lorenzo, Alberto; Cenador, María Begoña García; Pinto, Sandra; Gupta, Rajeev; et al

Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation ↗

Nature Communications, 1, 2017

Monteiro LM; Vasques-Nóvoa F; Ferreira L; Pinto-do-Ó P; Nascimento DS

Restoring heart function and electrical integrity: closing the circuit. ↗

NPJ Regenerative medicine, 2017

Aday S; Zoldan J; Besnier M; Carreto L; Saif J; Fernandes R; Santos T; et al

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition. ↗

Nature communications, 2017

2016

Ferreira, Lino

Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development ↗

Applied In Vitro Toxicology, 2016

Blondel S; Egesipe AL; Picardi P; Jaskowiak AL; Notarnicola M; Ragot J; Tournois J; et al

Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation. ↗

Cell death & disease, 2016

Maleki H; Rai A; Pinto S; Evangelista M; Cardoso RM; Paulo C; Carvalheiro T; et al

High Antimicrobial Activity and Low Human Cell Cytotoxicity of Core-Shell Magnetic Nanoparticles Functionalized with an Antimicrobial Peptide. ↗

ACS applied materials & interfaces, 2016

Rai A; Pinto S; Evangelista MB; Gil H; Kallip S; Ferreira MG; Ferreira L

High-density antimicrobial peptide coating with broad activity and low cytotoxicity against human cells. ↗

Acta biomaterialia, 2016

Saraiva C; Paiva J; Santos T; Ferreira L; Bernardino L

MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease. ↗

Journal of controlled release : official journal of the Controlled Release Society, 2016

Santos T; Boto C; Saraiva CM; Bernardino L; Ferreira L

Nanomedicine Approaches to Modulate Neural Stem Cells in Brain Repair. ↗

Trends in biotechnology, 2016

Saraiva C; Praça C; Ferreira R; Santos T; Ferreira L; Bernardino L

Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases. ↗

Journal of controlled release : official journal of the Controlled Release Society, 2016

Rai A; Pinto S; Velho TR; Ferreira AF; Moita C; Trivedi U; Evangelista M; et al

One-step synthesis of high-density peptide-conjugated gold nanoparticles with antimicrobial efficacy in a systemic infection model. ↗

Biomaterials, 2016

Ferreira R; Fonseca MC; Santos T; Sargento-Freitas J; Tjeng R; Paiva F; Castelo-Branco M; Ferreira LS; Bernardino L

Retinoic acid-loaded polymeric nanoparticles enhance vascular regulation of neural stem cell survival and differentiation after ischaemia. ↗

Nanoscale, 2016

Aday S; Cecchelli R; Hallier-Vanuxeem D; Dehouck MP; Ferreira L

Stem Cell-Based Human Blood-Brain Barrier Models for Drug Discovery and Delivery. ↗

Trends in biotechnology, 2016

Saraiva C; Ferreira L; Bernardino L

Traceable microRNA-124 loaded nanoparticles as a new promising therapeutic tool for Parkinson's disease. ↗

Neurogenesis (Austin, Tex.), 2016

2015

Ferreira, Lino

An overview of new translational, clinical and therapeutic perspectives in laminopathies and other nuclear envelope-related diseases. Proceedings of the 1st French-Italian meeting on laminopathies & other nuclear envelope-related diseases

Orphanet Journal of Rare Diseases , 2015

Ferreira L

Development of a SMCs model from HGPS-iPS and proofs of principle. ↗

Orphanet journal of rare diseases, 2015

Kostic I; Fidalgo-Carvalho I; Aday S; Vazão H; Carvalheiro T; Grãos M; Duarte A; et al

Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions. ↗

Scientific reports, 2015

Esteves M; Cristóvão AC; Saraiva T; Rocha SM; Baltazar G; Ferreira L; Bernardino L

Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease. ↗

, 2015

Pitrez P; Rosa SC; Almeida C; Ferreira L

Vascular disease modeling using induced pluripotent stem cells: focus in Hutching-Gilford progeria syndrome. ↗

, 2015

2014

Lang, N.; Pereira, M.J.; Lee, Y.; Friehs, I.; Vasilyev, N.V.; Feins, E.N.; Ablasser, K.; et al

A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects ↗

Science Translational Medicine, 218, 2014

Cecchelli, R.; Aday, S.; Sevin, E.; Almeida, C.; Culot, M.; Dehouck, L.; Coisne, C.; et al

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells ↗

PLoS ONE, 6, 2014

Ricotti, L.; Das Neves, R.P.; Ciofani, G.; Canale, C.; Nitti, S.; Mattoli, V.; Mazzolai, B.; Ferreira, L.; Menciassi, A.

Boron nitride nanotube-mediated stimulation modulates F/G-actin ratio and mechanical properties of human dermal fibroblasts ↗

Journal of Nanoparticle Research, 2, 2014

Pereira, M.J.N.; Sundback, C.A.; Lang, N.; Cho, W.K.; Pomerantseva, I.; Ouyang, B.; Tao, S.L.; et al

Combined Surface Micropatterning and Reactive Chemistry Maximizes Tissue Adhesion with Minimal Inflammation ↗

Advanced Healthcare Materials, 4, 565-, 2014

Ferreira, Lino

Inflammatory modulation of stem cells by Magnetic Resonance Imaging (MRI)-detectable nanoparticles ↗

RSC Adv., 2014

Santos, S.M.; Dinis, A.M.; Peixoto, F.; Ferreira, L.; Jurado, A.S.; Videira, R.A.

Interaction of fullerene nanoparticles with biomembranes: From the partition in lipid membranes to effects on mitochondrial bioenergetics ↗

Toxicological Sciences, 1, 117-, 2014

Chereddy KK; Her CH; Comune M; Moia C; Lopes A; Porporato PE; Vanacker J; et al

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing. ↗

, 2014

2013

Pereira, M.J.N.; Ouyang, B.; Sundback, C.A.; Lang, N.; Friehs, I.; Mureli, S.; Pomerantseva, I.; et al

A highly tunable biocompatible and multifunctional biodegradable elastomer ↗

Advanced Materials, 8, 1209-, 2013

Lino, M.M.; Paulo, C.S.O.; Vale, A.C.; Vaz, M.F.; Ferreira, L.S.

Antifungal activity of dental resins containing amphotericin B-conjugated nanoparticles ↗

Dental Materials, 10, 2013

Ricotti, L.; Fujie, T.; Vazão, H.; Ciofani, G.; Marotta, R.; Brescia, R.; Filippeschi, C.; et al

Boron Nitride Nanotube-Mediated Stimulation of Cell Co-Culture on Micro-Engineered Hydrogels ↗

PLoS ONE, 8, 2013

Paulo, C.S.O.; Lino, M.M.; Matos, A.A.; Ferreira, L.S.

Differential internalization of amphotericin B - Conjugated nanoparticles in human cells and the expression of heat shock protein 70 ↗

Biomaterials, 21, 5281-, 2013

Gomes, R.S.M.; Neves, R.P.D.; Cochlin, L.; Lima, A.; Carvalho, R.; Korpisalo, P.; Dragneva, G.; et al

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial ↗

ACS Nano, 4, 3362-, 2013

2012

Ferreira R; Santos T; Gonçalves J; Baltazar G; Ferreira L; Agasse F; Bernardino L

Histamine modulates microglia function. ↗

, 2012

Bernardino, L.; Eiriz, M.F.; Santos, T.; Xapelli, S.; Grade, S.; Rosa, A.I.; Cortes, L.; et al

Histamine stimulates neurogenesis in the rodent subventricular zone ↗

Stem Cells, 4, 773-, 2012

Santos, T.; Maia, J.; Agasse, F.; Xapelli, S.; Ferreira, L.; Bernardino, L.

Nanomedicine boosts neurogenesis: New strategies for brain repair ↗

Integrative Biology (United Kingdom), 9, 973-, 2012

Botequim, D.; Maia, J.; Lino, M.M.F.; Lopes, L.M.F.; Simões, P.N.; Ilharco, L.M.; Ferreira, L.

Nanoparticles and surfaces presenting antifungal, antibacterial and antiviral properties ↗

Langmuir, 20, 7646-, 2012

Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Bragancia, J.; et al

Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain ↗

ACS Nano, 12, 10463-, 2012

Ricotti, L.; Polini, A.; Genchi, G.G.; Ciofani, G.; Iandolo, D.; Vazão, H.; Mattoli, V.; et al

Proliferation and skeletal myotube formation capability of C2C12 and H9c2 cells on isotropic and anisotropic electrospun nanofibrous PHB scaffolds ↗

Biomedical Materials, 3, 2012

Maia, J.; Vazão, H.; Pedroso, D.C.S.; Jesus, C.S.H.; Brito, R.M.M.; Grãos, M.; Gil, M.H.; Ferreira, L.

VEGF-functionalized dextran has longer intracellular bioactivity than VEGF in endothelial cells ↗

Biomacromolecules, 9, 2906-, 2012

2011

Maia, J.; Santos, T.; Aday, S.; Agasse, F.; Cortes, L.; Malva, J.O.; Bernardino, L.; Ferreira, L.

Controlling the neuronal differentiation of stem cells by the intracellular delivery of retinoic acid-loaded nanoparticles ↗

ACS Nano, 1, 97-, 2011

Kraehenbuehl, T.P.; Ferreira, L.S.; Hayward, A.M.; Nahrendorf, M.; van der Vlies, A.J.; Vasile, E.; Weissleder, R.; Langer, R.; Hubbell, J.A.

Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction ↗

Biomaterials, 4, 1102-, 2011

Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells ↗

PLoS ONE, 1, 2011

Paulo, C.S.O.; Pires Das Neves, R.; Ferreira, L.S.

Nanoparticles for intracellular-targeted drug delivery ↗

Nanotechnology, 49, 2011

Pereira, M.J.N.; Carvalho, I.F.; Karp, J.M.; Ferreira, L.S.

Sensing the cardiac environment: Exploiting cues for regeneration ↗

Journal of Cardiovascular Translational Research, 5, 616-, 2011

Kraehenbuehl, T.P.; Langer, R.; Ferreira, L.S.

Three-dimensional biomaterials for the study of human pluripotent stem cells ↗

Nature Methods, 9, 731-, 2011

Vazão, H.; das Neves, R.P.; Grãos, M.; Ferreira, L.

Towards the maturation and characterization of smooth muscle cells derived from human embryonic stem cells ↗

PLoS ONE, 3, 2011

2010

Paulo, C.S.O.; Vidal, M.; Ferreira, L.S.

Antifungal nanoparticles and surfaces ↗

Biomacromolecules, 10, 2810-, 2010

Levenberg, S.; Ferreira, L.S.; Chen-Konak, L.; Kraehenbuehl, T.P.; Langer, R.

Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells. ↗

Nature protocols, 6, 1115-, 2010

Ferreira, L.; Pedroso, D.C.S.; Vazão, H.; Gomes, R.S.M.

Stem cell-based therapies for heart regeneration: What did the bench teach us? ↗

Cardiovascular and Hematological Disorders - Drug Targets, 3, 173-, 2010

Gerecht, S.; Ferreira, L.S.; Langer, R.; Gerecht S; Ferreira LS; Langer R

Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds. ↗

Methods in molecular biology (Clifton, N.J.), 333-, 2010

2009

Kraehenbuehl, T.P.; Ferreira, L.S.; Zammaretti, P.; Hubbell, J.A.; Langer, R.

Cell-responsive hydrogel for encapsulation of vascular cells ↗

Biomaterials, 26, 4318-, 2009

Ferreira, L.

Nanoparticles as tools to study and control stem cells ↗

Journal of Cellular Biochemistry, 4, 746-, 2009

Ferreira, L.; Zumbuehl, A.

Non-leaching surfaces capable of killing microorganisms on contact ↗

Journal of Materials Chemistry, 42, 7796-, 2009

2008

Mahdavi, A.; Ferreira, L.; Sundback, C.; Nichol, J.W.; Chan, E.P.; Carter, D.J.D.; Bettinger, C.J.; et al

2007

Zumbuehl, A.; Ferreira, L.; Kuhn, D.; Astashkina, A.; Long, L.; Yeo, Y.; Iaconis, T.; et al

Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle-like cells and form vascular networks in vivo ↗

Circulation Research, 3, 286-, 2007

2006

Khademhosseini, A.; Ferreira, L.; Blumling III, J.; Yeh, J.; Karp, J.M.; Fukuda, J.; Langer, R.

2005

Ferreira, L.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S.

Biocatalytic synthesis of highly ordered degradable dextran-based hydrogels ↗

Biomaterials, 23, 4707-, 2005

Ferreira, L.; Evangelista, M.B.; Martins, M.C.L.; Granja, P.L.; Esteves, J.L.; Barbosa, M.A.

Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: Surface characterization and pull-out tests ↗

Polymer, 23, 9840-, 2005

Maia, J.; Ferreira, L.; Carvalho, R.; Ramos, M.A.; Gil, M.H.

Synthesis and characterization of new injectable and degradable dextran-based hydrogels ↗

Polymer, 23, 9604-, 2005

2004

Ferreira, L.; Rafael, A.; Lamghari, M.; Barbosa, M.A.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S.

Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels ↗

Journal of Biomedical Materials Research - Part A, 3, 584-, 2004

2003

Ferreira, L.; Ramos, M.A.; Dordick, J.S.; Gil, M.H.

Influence of different silica derivatives in the immobilization and stabilization of a Bacillus licheniformis protease (Subtilisin Carlsberg) ↗

Journal of Molecular Catalysis B: Enzymatic, 4-6, 189-, 2003

2002

Ferreira, L.; Gil, M.H.; Carvalho, R.; Geraldes, C.F.G.C.; Kim, D.-Y.; Dordick, J.S.

2001

Ferreira, Lino

Design of a drug-delivery system based on polyacrylamide hydrogels. Evaluation of structural properties ↗

Chemical educator, 2001

2000

Ferreira, L.; Vidal, M.M.; Gil, M.H.

Evaluation of poly(2-hydroxyethyl methacrylate) gels as drug delivery systems at different pH values ↗

International Journal of Pharmaceutics, 2, 169-, 2000

Ferreira, L.; Vidal, M.M.; Geraldes, C.F.G.C.; Gil, M.H.

Preparation and characterization of gels based on sucrose modified with glycidyl methacrylate ↗

Carbohydrate Polymers, 1, 15-, 2000

Patents

2020

Ferreira, Lino

A light-triggerable nanoparticle library of formulations for the controlled release of RNAs

PCT/IB2020/05458, 2020

Ferreira, Lino

Light triggerable gene editing formulation, in vivo editing method, and used thereof

PCT/IB2020/05485, 2020

2018

Ferreira, Lino

Composition and method of stem cells for preservation of cardiac tissue

US20180135017, 2018

2017

Ferreira, Lino

Use of umbilical cord blood derived exosomes for tissue repair

WO2017163132A2, 2017

2015

Ferreira, Lino

Antimicrobial complexes

EP2838360A1, 2015

2014

Ferreira, Lino

A human blood-brain barrier model derived from stem cells

WO2014203087A1, 2014

Ferreira, Lino

Antimicrobial coating compositions

WO2014041508A1, 2014

2013

Ferreira, Lino

Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition, system, kit and uses thereof

WO2014097192, 2013

2012

Ferreira, Lino

Nanoparticles and uses thereof

PCT/EP2012/06555, 2012

2011

Ferreira, Lino

Composition and method to improve the therapeutic effect of stem cells

PCT/IB2011/05534, 2011

2010

Ferreira, Lino

Antimicrobial nanoparticle conjugate

10398005.8, 2010

2009

Ferreira, Lino

Adhesive articles

WO2009067482, 2009

Ferreira, Lino

Particulate delivery vehicles for embryoid bodies

WO2009100128, 2009

2007

Ferreira, Lino

Amplification of cell populations from embryonic stem cells

WO 2007022348, 2007

Ferreira, Lino

Coating of devices with effector compounds

WO2008005297, 2007

Ferreira, Lino

Development of Multifunctional Photocurable Degradable Elastomers

WO2007082304, 2007

Ferreira, Lino

Formation of vascular networks using human embryonic stem cells

WO2007140340, 2007

Ferreira, Lino

Medical devices and coatings with non-leaching bioactive peptides

WO2007095393, 2007